Jerauld S. Skotnicki

mTOR, a novel target in breast cancer: the effect of CCI-779, an mTOR inhibitor, in preclinical models of breast cancer.

Ker Yu, Lourdes Toral‐Barza, Carolyn Discafani et al. · Endocrine Related Cancer · 2001 · 418 citations · Full text

Breast Oncology, Cell Cycle, Cancer Biology +16

Reactions of sodium borohydride in acidic media. I. Reduction of indoles and alkylation of aromatic amines with carboxylic acids

Gordon W. Gribble, Pierre D. Lord, Jerauld S. Skotnicki et al. · Journal of the American Chemical Society · 1974 · 240 citations

Acidic Media, Chemical Engineering, Engineering +12

Binding of rapamycin analogs to calcium channels and FKBP52 contributes to their neuroprotective activities

Benfang Helen Ruan, Kevin Pong, Flora Jow et al. · Proceedings of the National Academy of Sciences · 2007 · 111 citations · Full text

Immunophilin Ligands, Cell Death, Synaptic Signaling +21

Biosynthesis of the immunosuppressants FK506, FK520, and rapamycin involves a previously undescribed family of enzymes acting on chorismate

Jennifer N. Andexer, Steven G. Kendrew, Mohammad Nur‐e‐Alam et al. · Proceedings of the National Academy of Sciences · 2011 · 107 citations · Full text

Potent, selective, and orally bioavailable matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis

Yonghan Hu, Jason Xiang, Martin DiGrandi et al. · Bioorganic & Medicinal Chemistry · 2005 · 107 citations

Medicine, Chronic Musculoskeletal Condition, Osteoarthritis +3