Binding of rapamycin analogs to calcium channels and FKBP52 contributes to their neuroprotective activities

Benfang Helen Ruan, Kevin Pong, Flora Jow, +20

Proceedings of the National Academy of Sciences

Immunophilin LigandsCell DeathSynaptic SignalingNeuroinflammationMolecular Pharmacology +19

Attenuation of Staurosporine-Induced Apoptosis, Oxidative Stress, and Mitochondrial Dysfunction by Synthetic Superoxide Dismutase and Catalase Mimetics, in Cultured Cortical Neurons

Kevin Pong, Susan R. Doctrow, Karl Huffman, +2

Experimental Neurology

Reductive StressBiochemistryMitochondrial DysfunctionMedicineLipid Peroxidation +9

Prevention of 1-methyl-4-phenylpyridinium- and 6-hydroxydopamine-induced nitration of tyrosine hydroxylase and neurotoxicity by EUK-134, a superoxide dismutase and catalase mimetic, in cultured dopaminergic neurons

Kevin Pong, Susan R. Doctrow, Michel Baudry

Brain Research

Tyrosine HydroxylaseBiochemistryMedicineCultured Dopaminergic NeuronsNeuropharmacology +10

Inhibition of Phosphatidylinositol 3‐Kinase Activity Blocks Cellular Differentiation Mediated by Glial Cell Line‐Derived Neurotrophic Factor in Dopaminergic Neurons

Kevin Pong, Ren Xu, Will Baron, +2

Journal of Neurochemistry

Glial BiologyCellular NeurobiologySynaptic SignalingSocial SciencesPhosphatidylinositol 3‐Kinase +15

Expression of NALP1 in cerebellar granule neurons stimulates apoptosis

Feng Liu, C. Frederick Lo, Xiaoping Ning, +11

Cellular Signalling

Signal TransductionCell SignalingApoptosisAutophagyCell Death +6

Neurotrophin-4/5 treatment reduces infarct size in rats with middle cerebral artery occlusion

K.M.John Chan, Diem-Thuy N. Lam, Kevin Pong, +2

Neurochemical Research

ThrombosisIschemic StrokeStrokeMedicineCerebrovascular Disease +11

Neuroprotective Profile of Novel Src Kinase Inhibitors in Rodent Models of Cerebral Ischemia

Shi Liang, Kevin Pong, Cathleen Gonzales, +12

Journal of Pharmacology and Experimental Therapeutics

Attenuation of zinc-induced intracellular dysfunction and neurotoxicity by a synthetic superoxide dismutase/catalase mimetic, in cultured cortical neurons

Kevin Pong, Yongqi Rong, Susan R. Doctrow, +1

Brain Research

NeurophysiologyZinc-induced Intracellular DysfunctionCultured Cortical NeuronsMedicineSynthetic Superoxide Dismutase/catalase +10

Screening of immunophilin ligands by quantitative analysis of neurofilament expression and neurite outgrowth in cultured neurons and cells

Danni Liu, H. Beal McIlvain, Myles Fennell, +5

Journal of Neuroscience Methods

Immunophilin LigandsImmunologyQuantitative AnalysisBrain-immune InteractionCytoskeleton +8

Inhibition of Glial Cell Line‐Derived Neurotrophic Factor Induced Intracellular Activity by K‐252b on Dopaminergic Neurons

Kevin Pong, Ren Xu, Klaus D. Beck, +2

Journal of Neurochemistry