H. Artee Luchman

Gradient of Developmental and Injury Response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneity

Laura M. Richards, Owen Whitley, Graham MacLeod et al. · Nature Cancer · 2021 · 306 citations

Neuro-oncology, Transcriptional Regulation, Lineage Plasticity +10

Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells

Graham MacLeod, Danielle Bozek, Nishani Rajakulendran et al. · Cell Reports · 2019 · 237 citations · Full text

Engineering, Genetics, Glioma +17

PRMT5 inhibition disrupts splicing and stemness in glioblastoma

Patty Sachamitr, Jolene Caifeng Ho, Felipe E. Ciamponi et al. · Nature Communications · 2021 · 205 citations · Full text

Lactate dehydrogenase A silencing in IDH mutant gliomas

Charles Chesnelong, Myriam M. Chaumeil, Michael Blough et al. · Neuro-Oncology · 2013 · 198 citations · Full text

An in vivo patient-derived model of endogenous IDH1-mutant glioma

H. Artee Luchman, O. D. Stechishin, Nam H. Dang et al. · Neuro-Oncology · 2011 · 180 citations · Full text

Tumor Biology, Neuro-oncology, Somatic Mutations +13