Hiroyuki Sayama

Application of a Physiologically Based Pharmacokinetic Model Informed by a Top-Down Approach for the Prediction of Pharmacokinetics in Chronic Kidney Disease Patients

Hiroyuki Sayama, Hiroaki Takubo, Hiroshi Komura et al. · The AAPS Journal · 2014 · 54 citations · Full text

Translational Medicine, Renal Function, Physiologically Based Pharmacokinetics +9

A Quantitative Systems Pharmacology Consortium Approach to Managing Immunogenicity of Therapeutic Proteins

Andrzej Kierzek, Timothy P. Hickling, Isabel Figueroa et al. · CPT Pharmacometrics & Systems Pharmacology · 2019 · 30 citations · Full text

Application of Hybrid Approach Based on Empirical and Physiological Concept for Predicting Pharmacokinetics in Humans—Usefulness of Exponent on Prospective Evaluation of Predictability

Hiroyuki Sayama, Hiroshi Komura, Motohiro Kogayu · Drug Metabolism and Disposition · 2012 · 19 citations

Development of a Hybrid Physiologically Based Pharmacokinetic Model with Drug‐Specific Scaling Factors in Rat to Improve Prediction of Human Pharmacokinetics

Hiroyuki Sayama, Hiroshi Komura, Motohiro Kogayu et al. · Journal of Pharmaceutical Sciences · 2013 · 15 citations

Molecular Pharmacology, Physiologically Based Pharmacokinetics, Pharmacokinetic Modeling +9

Virtual clinical trial simulations for a novel KRAS^G12C inhibitor (ASP2453) in non‐small cell lung cancer

Hiroyuki Sayama, Diana H. Marcantonio, Takeyuki Nagashima et al. · CPT Pharmacometrics & Systems Pharmacology · 2021 · 15 citations · Full text