Concepedia

Hiroaki Takubo

HT

Statistics

Publications

5

Citations

279

H-Index

5

Active since

1998

Affiliations

Japan Tobacco (Japan)(Current)

Tokyo University of Pharmacy and Life Sciences

Hiroaki Takubo is an author at Japan Tobacco (Japan) specializing in pharmacology, pharmacy, and pharmacokinetics.

Publications per year

1998–2018

5

Publications

5

A Possible Mechanism of Eighteen Patient Deaths Caused by Interactions of Sorivudine, a New Antiviral Drug, with Oral 5-Fluorouracil Prodrugs

Haruhiro Okuda, Kenichiro Ogura, Atsushi Kato et al. · Journal of Pharmacology and Experimental Therapeutics · 1998 · 155 citations

, , +14

Application of a Physiologically Based Pharmacokinetic Model Informed by a Top-Down Approach for the Prediction of Pharmacokinetics in Chronic Kidney Disease Patients

Hiroyuki Sayama, Hiroaki Takubo, Hiroshi Komura et al. · The AAPS Journal · 2014 · 55 citations

, , +15

Suicidal inactivation of human dihydropyrimidine dehydrogenase by (E)-5-(2-bromovinyl)uracil derived from the antiviral, sorivudine

Kenichiro Ogura, Takahito Nishiyama, Hiroaki Takubo et al. · Cancer Letters · 1998 · 40 citations

, , +8

Prediction of human pharmacokinetics of typical compounds by a physiologically based method using chimeric mice with humanized liver

Keigo Nakayama, Soichiro Ito, Masahiro Suzuki et al. · Xenobiotica · 2018 · 19 citations · Full text

, , +17

Characterization of gastrointestinal absorption of digoxin involving influx and efflux transporter in rats: application of<i>mdr1a</i>knockout (−/−) rats into absorption study of multiple transporter substrate

Motoya Suzuki, Hiroshi Komura, Tomonori Yoshikawa et al. · Xenobiotica · 2014 · 10 citations

, , +17

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