Concepedia

Diane K. Luci

DK

17

Publications

1.4K

Citations

16

H-Index

2007

Active since

Affiliations

National Center for Advancing Translational Sciences(Current)

National Institutes of Health

Johnson & Johnson (United States)

University of California, Santa Cruz

Thomas Jefferson University

Diane K. Luci is an author at National Center for Advancing Translational Sciences specializing in medicine, drug discovery, and biochemistry.

Top concepts

MedicineBiochemistryDrug DiscoveryPharmacologyNatural SciencesMedicinal ChemistryPharmacotherapyChemical BiologyMolecular BiologyMolecular Pharmacology

Publications per year

2007–2023

17

Publications

17

A selective USP1–UAF1 inhibitor links deubiquitination to DNA damage responses

Liang Qin, Thomas S. Dexheimer, Ping Zhang et al. · Nature Chemical Biology · 2014 · 265 citations · Full text

Genome Instability, Genomic Mechanism, Molecular Biology +2

Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy

William C. Stafford, Xiaoxiao Peng, Maria Hägg Olofsson et al. · Science Translational Medicine · 2018 · 229 citations · Full text

Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH)

Ganesha Rai, Kyle R. Brimacombe, Bryan T. Mott et al. · Journal of Medicinal Chemistry · 2017 · 146 citations · Full text

Disrupting malaria parasite AMA1–RON2 interaction with a small molecule prevents erythrocyte invasion

P. Srinivasan, Adam Yasgar, Diane K. Luci et al. · Nature Communications · 2013 · 113 citations · Full text

Antiparasitic Agent, Malaria, Immunology +7

First Selective 12-LOX Inhibitor, ML355, Impairs Thrombus Formation and Vessel Occlusion In Vivo With Minimal Effects on Hemostasis

Reheman Adili, Benjamin E. Tourdot, K. Mast et al. · Arteriosclerosis Thrombosis and Vascular Biology · 2017 · 105 citations · Full text

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