Brandon J. Margolis

Design, synthesis, structure–activity relationship, and in vivo activity of azabicyclic aryl amides as α7 nicotinic acetylcholine receptor agonists

Daniel P. Walker, Donn G. Wishka, David W. Piotrowski et al. · Bioorganic & Medicinal Chemistry · 2006 · 94 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Assembly of 4-Aminoquinolines via Palladium Catalysis:  A Mild and Convenient Alternative to S_NAr Methodology

Brandon J. Margolis, Kimberly A. Long, Dana L. T. Laird et al. · The Journal of Organic Chemistry · 2007 · 73 citations

Natural Sciences, Chemistry, Medicinal Chemistry +8

An Efficient Assembly of Heterobenzazepine Ring Systems Utilizing an Intramolecular Palladium-Catalyzed Cycloamination

Brandon J. Margolis, Jacob J. Swidorski, Bruce N. Rogers · The Journal of Organic Chemistry · 2002 · 56 citations

Natural Sciences, Chemistry, Medicinal Chemistry +10

Discovery of <i>N</i>-(6-Fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3<i>R</i>)-3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide (LSN 3213128), a Potent and Selective Nonclassical Antifolate Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase (AICARFT) Inhibitor Effective at Tumor Suppression in a Cancer Xenograft Model

Kevin R. Fales, F. George Njoroge, Harold B. Brooks et al. · Journal of Medicinal Chemistry · 2017 · 33 citations · Full text

Medicine, Oncology, Pharmacology +14

Investigating the Behavior of Published PAINS Alerts Using a Pharmaceutical Company Data Set

Lewis R. Vidler, Ian A. Watson, Brandon J. Margolis et al. · ACS Medicinal Chemistry Letters · 2018 · 32 citations · Full text

Pharmacy, Medicinal Chemistry, Drug Design +9