Christina Ries

In Vivo Active Aldosterone Synthase Inhibitors with Improved Selectivity: Lead Optimization Providing a Series of Pyridine Substituted 3,4-Dihydro-1<i>H</i>-quinolin-2-one Derivatives

Simon Lucas, Ralf Heim, Christina Ries et al. · Journal of Medicinal Chemistry · 2008 · 78 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Novel Aldosterone Synthase Inhibitors with Extended Carbocyclic Skeleton by a Combined Ligand-Based and Structure-Based Drug Design Approach

Simon Lucas, Ralf Heim, Matthias Negri et al. · Journal of Medicinal Chemistry · 2008 · 72 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Overcoming Undesirable CYP1A2 Inhibition of Pyridylnaphthalene-Type Aldosterone Synthase Inhibitors: Influence of Heteroaryl Derivatization on Potency and Selectivity

Ralf Heim, Simon Lucas, Cornelia M. Grombein et al. · Journal of Medicinal Chemistry · 2008 · 49 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Selective aldosterone synthase inhibitors reduce aldosterone formation in vitro and in vivo

Christina Ries, Simon Lucas, Ralf Heim et al. · The Journal of Steroid Biochemistry and Molecular Biology · 2009 · 23 citations

Life Sciences, Endocrinology, Pharmacology +12

Facile Synthesis of Chrysin-derivatives with Promising Activities as Aromatase Inhibitors ^†

Hamdoon A. Mohammed, Lalla A. Ba, Torsten Burkholz et al. · Natural Product Communications · 2011 · 22 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12