Concepedia

Cornelia M. Grombein

CM

3

Publications

100

Citations

3

H-Index

2008

Active since

Affiliations

Saarland University(Current)

Helmholtz Institute for Pharmaceutical Research Saarland

Cornelia M. Grombein is an author at Saarland University specializing in drug discovery, natural sciences, and medicinal chemistry.

Top concepts

MedicineBiochemistryPharmacologyDrug DiscoveryNatural SciencesMedicinal ChemistryPharmacotherapyDrug DevelopmentPhysiologyBioorganic Chemistry

Publications per year

2008–2014

3

Publications

3

Overcoming Undesirable CYP1A2 Inhibition of Pyridylnaphthalene-Type Aldosterone Synthase Inhibitors: Influence of Heteroaryl Derivatization on Potency and Selectivity

Ralf Heim, Simon Lucas, Cornelia M. Grombein et al. · Journal of Medicinal Chemistry · 2008 · 49 citations · Full text

Medicinal Chemistry, Undesirable Cyp1a2 Inhibition, Biochemistry +15

1-Phenylsulfinyl-3-(pyridin-3-yl)naphthalen-2-ols: A new class of potent and selective aldosterone synthase inhibitors

Cornelia M. Grombein, Qingzhong Hu, Ralf Heim et al. · European Journal of Medicinal Chemistry · 2014 · 27 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Aldo-keto Reductase +11

Heteroatom insertion into 3,4-dihydro-1H-quinolin-2-ones leads to potent and selective inhibitors of human and rat aldosterone synthase

Cornelia M. Grombein, Qingzhong Hu, Sabrina Rau et al. · European Journal of Medicinal Chemistry · 2014 · 24 citations · Full text

Medicinal Chemistry, Aldo-keto Reductase, Biochemistry +8

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