Constance M. Yuan

T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial

Daniel W Lee, James N. Kochenderfer, Maryalice Stetler‐Stevenson et al. · The Lancet · 2014 · 2.9K citations

Life Sciences, Hematology, Oncology +17

CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy

Terry J. Fry, Nirali N. Shah, Rimas J. Orentas et al. · Nature Medicine · 2017 · 1.3K citations

Life Sciences, Immunology, Oncology +14

The lymph node microenvironment promotes B-cell receptor signaling, NF-κB activation, and tumor proliferation in chronic lymphocytic leukemia

Yair Herishanu, Patricia Pérez‐Galán, Delong Liu et al. · Blood · 2010 · 815 citations

Medicine, Molecular Biology, Oncology +16

T Cells Genetically Modified to Express an Anti–B-Cell Maturation Antigen Chimeric Antigen Receptor Cause Remissions of Poor-Prognosis Relapsed Multiple Myeloma

Jennifer N. Brudno, Irina Marić, Steven D. Hartman et al. · Journal of Clinical Oncology · 2018 · 791 citations · Full text

Medicine, Hematology, Immunology +15

Anti-CD22–chimeric antigen receptors targeting B-cell precursor acute lymphoblastic leukemia

Waleed Haso, Daniel W. Lee, Nirali N. Shah et al. · Blood · 2012 · 583 citations · Full text

Medicine, Immunology, Oncology +9