Emily C. Brock

Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis

Carolyn M. Walsh, Rose Z. Hill, Jamie Schwendinger‐Schreck et al. · eLife · 2019 · 149 citations · Full text

Inflammation, Cytokine, Atopic Dermatitis +14

Mast Cell and Eosinophil Activation Are Associated With COVID-19 and TLR-Mediated Viral Inflammation: Implications for an Anti-Siglec-8 Antibody

Simon Gebremeskel, Julia Schanin, Krysta M. Coyle et al. · Frontiers in Immunology · 2021 · 106 citations · Full text

AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice

Bradford A. Youngblood, Emily C. Brock, John Leung et al. · International Archives of Allergy and Immunology · 2019 · 104 citations · Full text

Siglec-8 antibody reduces eosinophils and mast cells in a transgenic mouse model of eosinophilic gastroenteritis

Bradford A. Youngblood, Emily C. Brock, John Leung et al. · JCI Insight · 2019 · 103 citations · Full text

Immunodeficiencies, Immunology, Gastroenterology +19

A monoclonal antibody to Siglec-8 suppresses non-allergic airway inflammation and inhibits IgE-independent mast cell activation

Julia Schanin, Simon Gebremeskel, Wouter Korver et al. · Mucosal Immunology · 2020 · 73 citations · Full text

Asthma, Inflammatory Lung Disease, Lung Inflammation +25