AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice - Concepedia

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AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice

DOI Full Paper Access

104

Citations

17

References

2019

Year

Bradford A. Youngblood, Emily C. Brock, John Leung, Rustom Falahati, Paul Bryce, Jessica Bright, J.C. Williams, Leonard D. Shultz, Dale L. Greiner, Michael A. Brehm,

International Archives of Allergy and Immunology

Abstract

AK002 selectively evokes potent apoptotic and ADCC activity against eosinophils and prevents systemic anaphylaxis through mast cell inhibition.

References

	Year	Citations

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