Michael J. Jurczak

Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity

Jorge Henao‐Mejia, Eran Elinav, Chengcheng Jin et al. · Nature · 2012 · 2.4K citations

Inflammation, Inflammasome-mediated Dysbiosis, Immunology +6

Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase

Anila K. Madiraju, Derek M. Erion, Yasmeen Rahimi et al. · Nature · 2014 · 1.3K citations · Full text

Mitochondrial Function, Biochemistry, Physiology +6

Ablation of PRDM16 and Beige Adipose Causes Metabolic Dysfunction and a Subcutaneous to Visceral Fat Switch

Paul Cohen, Julia D. Levy, Yingying Zhang et al. · Cell · 2014 · 872 citations · Full text

Obesity, Metabolic Syndrome, Body Composition +13

Hepatic Acetyl CoA Links Adipose Tissue Inflammation to Hepatic Insulin Resistance and Type 2 Diabetes

Rachel J. Perry, João Paulo Camporez, Romy Kursawe et al. · Cell · 2015 · 693 citations · Full text

Obesity, Metabolic Syndrome, Insulin Signaling +15

PKM2 Isoform-Specific Deletion Reveals a Differential Requirement for Pyruvate Kinase in Tumor Cells

William J. Israelsen, Talya L. Dayton, Shawn M. Davidson et al. · Cell · 2013 · 539 citations · Full text