Sarah J. Backe

Structural and Functional Regulation of Lactate dehydrogenase-A in Cancer

Mark R. Woodford, Victor Zitian Chen, Sarah J. Backe et al. · Future Medicinal Chemistry · 2020 · 57 citations

Aldo-keto Reductase, Apoptosis, Glycobiology +19

Chemical Perturbation of Oncogenic Protein Folding: from the Prediction of Locally Unstable Structures to the Design of Disruptors of Hsp90–Client Interactions

Antonella Paladino, Mark R. Woodford, Sarah J. Backe et al. · Chemistry - A European Journal · 2020 · 56 citations · Full text

Post-translational Regulation of FNIP1 Creates a Rheostat for the Molecular Chaperone Hsp90

Rebecca Sager, Mark R. Woodford, Sarah J. Backe et al. · Cell Reports · 2019 · 51 citations · Full text

The tumor suppressor folliculin inhibits lactate dehydrogenase A and regulates the Warburg effect

Mark R. Woodford, Alexander J. Baker-Williams, Rebecca Sager et al. · Nature Structural & Molecular Biology · 2021 · 36 citations · Full text

Cancer Research, Cell Regulation, Medicine +10

A specialized Hsp90 co-chaperone network regulates steroid hormone receptor response to ligand

Sarah J. Backe, Rebecca Sager, Bethany R. Regan et al. · Cell Reports · 2022 · 32 citations · Full text

Molecular Biology, Hsp90 Client Activity, Hormone Receptor Response +18