Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries

Miljan Kuljanin, Dylan C. Mitchell, Devin K. Schweppe, +9

Nature Biotechnology

BiochemistryMolecular Biological MethodNatural SciencesMedicineBioanalysis +10

Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules

Behnam Nabet, Fleur M. Ferguson, Bo Kyung A. Seong, +10

Nature Communications

Reuterin in the healthy gut microbiome suppresses colorectal cancer growth through altering redox balance

Hannah N. Bell, Ryan J. Rebernick, Joshua Goyert, +14

Cancer Cell

ProbioticDysbiosisRedox BalancePathologyColorectal Cancer +8

Neurons Release Serine to Support mRNA Translation in Pancreatic Cancer

Robert S. Banh, Douglas E. Biancur, Keisuke Yamamoto, +9

Cell

Neurons Release SerineSignal TransductionMolecular NeurosciencePancreatic CancerMedicine +6

A proteome-wide atlas of drug mechanism of action

Dylan C. Mitchell, Miljan Kuljanin, Jiaming Li, +5

Nature Biotechnology

BiochemistryMedicineNatural SciencesPharmacologyMechanism Of Action +3

Discovery of a selective inhibitor of doublecortin like kinase 1

Fleur M. Ferguson, Behnam Nabet, Srivatsan Raghavan, +34

Nature Chemical Biology

MedicineReceptor Tyrosine KinaseKinase 1PharmacologyCell Biology +3

Defining and Targeting Adaptations to Oncogenic KRASG12C Inhibition Using Quantitative Temporal Proteomics

Naiara Santana-Codina, Amrita Singh Chandhoke, Qijia Yu, +11

Cell Reports

Covalent disruptor of YAP-TEAD association suppresses defective Hippo signaling

Mengyang Fan, Wenchao Lu, Jianwei Che, +23

eLife

Collagenase treatment enhances proteomic coverage of low-abundance proteins in decellularized matrix bioscaffolds

Miljan Kuljanin, Cody Brown, Matthew J. Raleigh, +2

Biomaterials

Proteomic TechnologyDecellularized Matrix BioscaffoldsProtein FoldingMedicineNatural Sciences +10

High Aldehyde Dehydrogenase Activity Identifies a Subset of Human Mesenchymal Stromal Cells with Vascular Regenerative Potential

Stephen E. Sherman, Miljan Kuljanin, Tyler T. Cooper, +3

Stem Cells