Swati P. Mercer

Discovery of the Dual Orexin Receptor Antagonist [(7<i>R</i>)-4-(5-Chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2<i>H</i>-1,2,3-triazol-2-yl)phenyl]methanone (MK-4305) for the Treatment of Insomnia

Christopher D. Cox, Michael J. Breslin, David B. Whitman et al. · Journal of Medicinal Chemistry · 2010 · 367 citations · Full text

Psychotropic Medication, Pharmacotherapy, Primary Insomnia +17

Carboxylation and Mitsunobu Reaction of Amines to Give Carbamates:  Retention vs Inversion of Configuration Is Substituent-Dependent

Christopher J. Dinsmore, Swati P. Mercer · Organic Letters · 2004 · 101 citations

Carbon Dioxide, Engineering, Mitsunobu Reaction +8

Proline bis-amides as potent dual orexin receptor antagonists

Jeffrey M. Bergman, Anthony J. Roecker, Swati P. Mercer et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 71 citations · Full text

Proline Bis-amides, Biochemistry, Medicine +6

Discovery of 5′′‐Chloro‐<i>N</i>‐[(5,6‐dimethoxypyridin‐2‐yl)methyl]‐2,2′:5′,3′′‐terpyridine‐3′‐carboxamide (MK‐1064): A Selective Orexin 2 Receptor Antagonist (2‐SORA) for the Treatment of Insomnia

Anthony J. Roecker, Swati P. Mercer, John D. Schreier et al. · ChemMedChem · 2013 · 65 citations

Kinesin spindle protein (KSP) inhibitors. Part 8: Design and synthesis of 1,4-diaryl-4,5-dihydropyrazoles as potent inhibitors of the mitotic kinesin KSP

Anthony J. Roecker, Paul J. Coleman, Swati P. Mercer et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 40 citations · Full text

Biochemistry, Natural Sciences, Macromolecular Machine +7