<i>Kdm6a</i> Deficiency Activates Inflammatory Pathways, Promotes M2 Macrophage Polarization, and Causes Bladder Cancer in Cooperation with <i>p53</i> Dysfunction

Kohei Kobatake, Kenichiro Ikeda, Yuichiro Nakata, +18

Clinical Cancer Research

Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation

Reina Nagase, Daichi Inoue, Alessandro Pastore, +17

The Journal of Experimental Medicine

Hematological MalignancyKi MiceDevelopmental BiologyAdditional Sex CombsMedicine +13

Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg2

Takeshi Ueda, Akiko Nagamachi, Keiyo Takubo, +15

Blood

The Role of the Basic Helix-Loop-Helix Transcription Factor <i>Dec1</i> in the Regulatory T Cells

Kazuko Miyazaki, Masaki Miyazaki, Yun Guo, +6

The Journal of Immunology

Identification of Zfp521/ZNF521 as a cooperative gene for E2A-HLF to develop acute B-lineage leukemia

Norimasa Yamasaki, Kazuko Miyazaki, Akiko Nagamachi, +8

Oncogene

Hematological MalignancyMixed-phenotype Acute LeukemiaGeneticsAcute B-lineage LeukemiaMolecular Genetics +7

UTX maintains the functional integrity of the murine hematopoietic system by globally regulating aging-associated genes

Yasuyuki Sera, Yuichiro Nakata, Takeshi Ueda, +20

Blood

CIZ1, a p21^Cip1/Waf1‐interacting protein, functions as a tumor suppressor in vivo

Rio Nishibe, Wataru Watanabe, Takeshi Ueda, +6

FEBS Letters

Acquired expression of CblQ367P in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia

Yuichiro Nakata, Takeshi Ueda, Akiko Nagamachi, +15

Blood

Acquired Deficiency of A20 Results in Rapid Apoptosis, Systemic Inflammation, and Abnormal Hematopoietic Stem Cell Function

Akiko Nagamachi, Yuichiro Nakata, Takeshi Ueda, +9

PLoS ONE

Lymphocyte DevelopmentA20 ResultsImmunologyImmune RegulationCell Death +26

Propagation of trimethylated H3K27 regulated by polycomb protein EED is required for embryogenesis, hematopoietic maintenance, and tumor suppression

Takeshi Ueda, Yuichiro Nakata, Akiko Nagamachi, +10

Proceedings of the National Academy of Sciences