Haploinsufficiency of SAMD9L, an Endosome Fusion Facilitator, Causes Myeloid Malignancies in Mice Mimicking Human Diseases with Monosomy 7

Akiko Nagamachi, Hirotaka Matsui, Hiroya Asou, +9

Cancer Cell

Hematological MalignancyMonosomy 7MedicineMalignant Blood DisorderImmunology +8

SETBP1 mutations drive leukemic transformation in ASXL1-mutated MDS

Daichi Inoue, Jiro Kitaura, Hirotaka Matsui, +16

Leukemia

Setbp1 MutationsCancer GeneticsMedicineRadiation OncologyTumor Biology +1

Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg2

Takeshi Ueda, Akiko Nagamachi, Keiyo Takubo, +15

Blood

Identification of a common microdeletion cluster in 7q21.3 subband among patients with myeloid leukemia and myelodysplastic syndrome

Hiroya Asou, Hirotaka Matsui, Yuko Ozaki, +4

Biochemical and Biophysical Research Communications

Hematological MalignancyMyelodysplastic SyndromeMedicineHematologyPathology +6

A paralogous pair of mammalian host restriction factors form a critical host barrier against poxvirus infection

Xiangzhi Meng, Fushun Zhang, Bo Yan, +5

PLoS Pathogens

VaccinationRestriction FactorViral ReplicationHost FactorHost Response +13

Poly-ADP Ribosylation of Miki by tankyrase-1 Promotes Centrosome Maturation

Yuko Ozaki, Hirotaka Matsui, Hiroya Asou, +9

Molecular Cell

BiosynthesisProtein FunctionNatural SciencesProtein BiosynthesisMolecular Biology +5

Biological implications of somatic DDX41 p.R525H mutation in acute myeloid leukemia

Moe Kadono, Akinori Kanai, Akiko Nagamachi, +13

Experimental Hematology

Hematological MalignancyBiological ImplicationsSomatic VariantMedicineAcute Myeloid Leukemia +6

Accumulation of versican facilitates wound healing: Implication of its initial ADAMTS-cleavage site

Shamima Islam, Kantinan Chuensirikulchai, Saichit Khummuang, +7

Matrix Biology

Initial Adamts-cleavage SiteVersican FacilitatesWound AssessmentSkin SubstituteWound Care +6

Identification of Zfp521/ZNF521 as a cooperative gene for E2A-HLF to develop acute B-lineage leukemia

Norimasa Yamasaki, Kazuko Miyazaki, Akiko Nagamachi, +8

Oncogene

Hematological MalignancyMixed-phenotype Acute LeukemiaGeneticsAcute B-lineage LeukemiaMolecular Genetics +7

UTX maintains the functional integrity of the murine hematopoietic system by globally regulating aging-associated genes

Yasuyuki Sera, Yuichiro Nakata, Takeshi Ueda, +20

Blood