José Luís Fachi

Microbiota derived short chain fatty acids promote histone crotonylation in the colon through histone deacetylases

Rachel Fellows, Jérémy Denizot, Claudia Stellato et al. · Nature Communications · 2018 · 512 citations · Full text

Microbiota-derived acetate protects against respiratory syncytial virus infection through a GPR43-type 1 interferon response

Krist Helen Antunes, José Luís Fachi, Rosemeire de Paula et al. · Nature Communications · 2019 · 388 citations · Full text

Butyrate Protects Mice from Clostridium difficile-Induced Colitis through an HIF-1-Dependent Mechanism

José Luís Fachi, Jaqueline de Souza Felipe, Laís Passariello Pral et al. · Cell Reports · 2019 · 343 citations · Full text

Acetate coordinates neutrophil and ILC3 responses against <i>C. difficile</i> through FFAR2

José Luís Fachi, Cristiane Sécca, Patrícia Brito Rodrigues et al. · The Journal of Experimental Medicine · 2019 · 197 citations · Full text

Chronic Inflammatory Diseases, Acetate-ffar2 Augments Expression, Dysbiosis +23

Repression of the aryl-hydrocarbon receptor prevents oxidative stress and ferroptosis of intestinal intraepithelial lymphocytes

Vincent Peng, Raki Sudan, Alina Ulezko Antonova et al. · Immunity · 2023 · 141 citations · Full text

Inflammation, Gastrointestinal Peptide Hormone, Mucosal Immunology +9