Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders

Simone Brioschi, Wei-Le Wang, Vincent Peng, +22

Science

Lymphocyte DevelopmentAdaptive Immune SystemImmunologyBlood CellPathology +19

TREM2 drives microglia response to amyloid-β via SYK-dependent and -independent pathways

Shoutang Wang, Raki Sudan, Vincent Peng, +20

Cell

Inflammation-Independent PathwaysNeurodegenerative DiseasesMedicineMicroglia Response +7

The neutrotime transcriptional signature defines a single continuum of neutrophils across biological compartments

Ricardo Grieshaber‐Bouyer, Felix A. Radtke, Pierre Cunin, +88

Nature Communications

Subsets of ILC3−ILC1-like cells generate a diversity spectrum of innate lymphoid cells in human mucosal tissues

Marina Cella, Ramya Gamini, Cristiane Sécca, +21

Nature Immunology

InflammationIlc3−ilc1-like CellsAutoimmune DiseaseMucosal ImmunologyInnate Immune System +8

Gut CD4+ T cell phenotypes are a continuum molded by microbes, not by TH archetypes

Evgeny Kiner, Elijah Willie, Brinda Vijaykumar, +95

Nature Immunology

Mucosal ImmunologyTh ArchetypesT-regulatory CellPathogenesisImmunology +5

Repression of the aryl-hydrocarbon receptor prevents oxidative stress and ferroptosis of intestinal intraepithelial lymphocytes

Vincent Peng, Raki Sudan, Alina Ulezko Antonova, +9

Immunity

InflammationGastrointestinal Peptide HormoneMucosal ImmunologyIntestinal Intraepithelial LymphocytesImmunology +7

Multi-tissue single-cell analysis deconstructs the complex programs of mouse natural killer and type 1 innate lymphoid cells in tissues and circulation

Adelle P. McFarland, Adam Yalin, Shuang-Yin Wang, +10

Immunity

Type 1Mouse Natural KillerMulti-tissue Single-cell AnalysisAutoimmune DiseaseLymphocyte Development +8

A Cre-deleter specific for embryo-derived brain macrophages reveals distinct features of microglia and border macrophages

Simone Brioschi, Julia A. Belk, Vincent Peng, +16

Immunity

EpendymaMedicineBorder MacrophagesBrain-immune InteractionNeuroscience +5

Alterations in Fecal Microbiomes and Serum Metabolomes of Fatigued Patients With Quiescent Inflammatory Bowel Diseases

Nienke Z. Borren, Damian R. Plichta, Amit D. Joshi, +11

Clinical Gastroenterology and Hepatology

InflammationChronic Inflammatory DiseasesProbioticDysbiosisMucosal Immunology +11

Metformin selectively dampens the acute inflammatory response through an AMPK-dependent mechanism

Thomas S. Postler, Vincent Peng, Dev Bhatt, +1

Scientific Reports