Simone Brioschi

Comprehensive Profiling of an Aging Immune System Reveals Clonal GZMK+ CD8+ T Cells as Conserved Hallmark of Inflammaging

Denis A. Mogilenko, Oleg Shpynov, Prabhakar S. Andhey et al. · Immunity · 2020 · 637 citations · Full text

Inflammation, Autoimmune Disease, Adaptive Immune System +12

TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy

Martina Molgora, Ekaterina Esaulova, William Vermi et al. · Cell · 2020 · 605 citations · Full text

Cancer Immunosurveillance, Medicine, T-regulatory Cell +10

Age-related myelin degradation burdens the clearance function of microglia during aging

Shima Safaiyan, Nirmal Kannaiyan, Nicolas Snaidero et al. · Nature Neuroscience · 2016 · 580 citations · Full text

Alzheimer's Disease, Aging, Clearance Function +13

Skull and vertebral bone marrow are myeloid cell reservoirs for the meninges and CNS parenchyma

Andrea Cugurra, Tornike Mamuladze, Justin Rustenhoven et al. · Science · 2021 · 577 citations · Full text

Cell Reservoirs, Innate Immune System, Immunology +26

Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders

Simone Brioschi, Wei-Le Wang, Vincent Peng et al. · Science · 2021 · 421 citations · Full text

Lymphocyte Development, Adaptive Immune System, Immunology +21