Sonja Neimanis

Bidirectional Allosteric Communication between the ATP-Binding Site and the Regulatory PIF Pocket in PDK1 Protein Kinase

Jörg O. Schulze, Giorgio Saladino, Katrien Busschots et al. · Cell chemical biology · 2016 · 81 citations · Full text

Pdk1 Protein Kinase, Signal Transduction, Protein Function +12

Substrate-Selective Inhibition of Protein Kinase PDK1 by Small Compounds that Bind to the PIF-Pocket Allosteric Docking Site

Katrien Busschots, Laura A. Lopez-Garcia, Carmen Lammi et al. · Chemistry & Biology · 2012 · 80 citations

Protein Kinase Pdk1, Medicinal Chemistry, Protein Function +12

Allosteric Regulation of Protein Kinase PKCζ by the N-Terminal C1 Domain and Small Compounds to the PIF-Pocket

Laura A. Lopez-Garcia, Jörg O. Schulze, Wolfgang Fröhner et al. · Chemistry & Biology · 2011 · 65 citations

Signal Transduction, Molecular Physiology, Allosteric Regulation +14

InterAKTions with FKBPs - Mutational and Pharmacological Exploration

A. Fabian, Andreas März, Sonja Neimanis et al. · PLoS ONE · 2013 · 47 citations · Full text

Pharmacological Exploration, Pharmacotherapy, Cancer Biology +18

4-Benzimidazolyl-3-Phenylbutanoic Acids As Novel Pif-Pocket-Targeting Allosteric Inhibitors of Protein Kinase PKCζ

Wolfgang Fröhner, Laura A. Lopez-Garcia, Sonja Neimanis et al. · Journal of Medicinal Chemistry · 2011 · 34 citations · Full text

Drug Target, Bioorganic Chemistry, Protein Kinase Pkcζ +17