Kameshwari Ambati

L1 drives IFN in senescent cells and promotes age-associated inflammation

Marco De Cecco, Takahiro Ito, Anna P. Petrashen et al. · Nature · 2019 · 1.2K citations

Life Sciences, Cell Biology, Immunology +14

cGAS drives noncanonical-inflammasome activation in age-related macular degeneration

Nagaraj Kerur, Shin‐ichi Fukuda, Daipayan Banerjee et al. · Nature Medicine · 2017 · 294 citations · Full text

Medicine, Immunology, Ophthalmology +14

Cytoplasmic synthesis of endogenous <i>Alu</i> complementary DNA via reverse transcription and implications in age-related macular degeneration

Shin‐ichi Fukuda, Akhil Varshney, Benjamin J. Fowler et al. · Proceedings of the National Academy of Sciences · 2021 · 64 citations · Full text

Medicine, Genetics, Molecular Biology +15

<i>Alu</i> complementary DNA is enriched in atrophic macular degeneration and triggers retinal pigmented epithelium toxicity via cytosolic innate immunity

Shin‐ichi Fukuda, Siddharth Narendran, Akhil Varshney et al. · Science Advances · 2021 · 51 citations · Full text

Medicine, Genetics, Molecular Biology +13

DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs

Shao-Bin Wang, Siddharth Narendran, Shuichiro Hirahara et al. · Science Immunology · 2021 · 51 citations · Full text

Life Sciences, Immunology, Molecular Biology +17