Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)¹

Daniel J. Klionsky, Amal Kamal Abdel‐Aziz, Sara Abdelfatah, +1267

Autophagy

Characterization of LAMP1-labeled nondegradative lysosomal and endocytic compartments in neurons

Xiu‐Tang Cheng, Yuxiang Xie, Bing Zhou, +3

The Journal of Cell Biology

Molecular BiologyLamp1-labeled Nondegradative LysosomalCytoskeletonLamp1-positive OrganellesCellular Neurobiology +20

RIPK3 as a potential therapeutic target for Gaucher's disease

Einat B. Vitner, Ran Salomon, Tamar Farfel‐Becker, +6

Nature Medicine

Potential Therapeutic TargetReceptor Tyrosine KinaseAutophagyPathologyCell Death +3

Neuronal Soma-Derived Degradative Lysosomes Are Continuously Delivered to Distal Axons to Maintain Local Degradation Capacity

Tamar Farfel‐Becker, Joseph C. Roney, Xiu‐Tang Cheng, +3

Cell Reports

Cellular NeurobiologySocial SciencesDistal AxonsNeuroregenerationAutophagy +17

Contribution of brain inflammation to neuronal cell death in neuronopathic forms of Gaucher's disease

Einat B. Vitner, Tamar Farfel‐Becker, Raya Eilam, +2

Brain

Neuronal accumulation of glucosylceramide in a mouse model of neuronopathic Gaucher disease leads to neurodegeneration

Tamar Farfel‐Becker, Einat B. Vitner, Steven L. Kelly, +6

Human Molecular Genetics

Substrate Reduction TherapyGlucosylceramide AccumulationSocial SciencesNeuroregenerationAlzheimer's Disease +17

Spatial and temporal correlation between neuron loss and neuroinflammation in a mouse model of neuronopathic Gaucher disease

Tamar Farfel‐Becker, Einat B. Vitner, Sarah N.R. Pressey, +3

Human Molecular Genetics

Neurochemical BiomarkersSocial SciencesNeuroinflammationAlzheimer's DiseaseNeurology +17

Altered expression and distribution of cathepsins in neuronopathic forms of Gaucher disease and in other sphingolipidoses

Einat B. Vitner, H. Dekel, Hila Zigdon, +5

Human Molecular Genetics

Lipid-mediated motor-adaptor sequestration impairs axonal lysosome delivery leading to autophagic stress and dystrophy in Niemann-Pick type C

Joseph C. Roney, Sunan Li, Tamar Farfel‐Becker, +7

Developmental Cell

Cell AutophagyMitophagyCell TraffickingAutophagyNiemann-pick Type C +10

Induction of the type I interferon response in neurological forms of Gaucher disease

Einat B. Vitner, Tamar Farfel‐Becker, Natália Santos Ferreira, +4

Journal of Neuroinflammation