Concepedia

RIPK3 as a potential therapeutic target for Gaucher's disease

Einat B. Vitner, Ran Salomon, Tamar Farfel‐Becker, Anna Meshcheriakova, Mohammad Ali, Andrés D. Klein, Frances M. Platt, Timothy M. Cox, Anthony H. Futerman

Nature Medicine · 2014 · 161 citations · 41 references

DOI

Concepts

References

41

Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase

Liming Sun, Huayi Wang, Zhigao Wang et al. · Cell · 2012 · 2.7K citations · Full text

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Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

Young-Sik Cho, Sreerupa Challa, David Moquin et al. · Cell · 2009 · 2.4K citations · Full text

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RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis

Duanwu Zhang, Jing Shao, Juan Lin et al. · Science · 2009 · 1.9K citations

, , +16

Catalytic activity of the caspase-8–FLIPL complex inhibits RIPK3-dependent necrosis

Andrew Oberst, Christopher P. Dillon, Ricardo Weinlich et al. · Nature · 2011 · 1.3K citations

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The Death Domain Kinase RIP Mediates the TNF-Induced NF-κB Signal

Michelle A. Kelliher, Stefan Grimm, Yasumasa Ishida et al. · Immunity · 1998 · 1.1K citations · Full text

, , +14