Catalytic activity of the caspase-8–FLIPL complex inhibits RIPK3-dependent necrosis

Andrew Oberst, Christopher P. Dillon, Ricardo Weinlich, +6

Nature

InflammationSignal TransductionSignaling PathwayMedicineApoptosis +7

RETRACTED: Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells

Jennifer Martinez, Johann Almendinger, Andrew Oberst, +5

Proceedings of the National Academy of Sciences

RIPK1 and NF-κB signaling in dying cells determines cross-priming of CD8 ⁺ T cells

Nader Yatim, Hélène Jusforgues-Saklani, Susana Orozco, +6

Science

Mitochondrial inner membrane permeabilisation enables mt <scp>DNA</scp> release during apoptosis

Joel S. Riley, Giovanni Quarato, Catherine Cloix, +11

The EMBO Journal

Caspase 8 inhibits programmed necrosis by processing CYLD

Marie Anne O’Donnell, Eva Pérez-Jiménez, Andrew Oberst, +5

Nature Cell Biology

InflammationThrombosisAutoimmune DiseaseCaspase 8Apoptosis +3

Limited Mitochondrial Permeabilization Causes DNA Damage and Genomic Instability in the Absence of Cell Death

Gabriel Ichim, Jonathan Lopez, Shafiq U. Ahmed, +17

Molecular Cell

MitophagyDna DamageGeneticsApoptosisMolecular Biology +15

Characterization of RIPK3-mediated phosphorylation of the activation loop of MLKL during necroptosis

Diego A. Rodríguez, Ricardo Weinlich, S. M. Brown, +9

Cell Death and Differentiation

Ripk3-mediated PhosphorylationSignal TransductionCell RegulationActivation LoopApoptosis +8

Intratumoral activation of the necroptotic pathway components RIPK1 and RIPK3 potentiates antitumor immunity

Annelise G. Snyder, Nicholas Hubbard, Michelle N. Messmer, +7

Science Immunology

RIPK3 Activates Parallel Pathways of MLKL-Driven Necroptosis and FADD-Mediated Apoptosis to Protect against Influenza A Virus

Shoko Nogusa, Roshan J. Thapa, Christopher P. Dillon, +19

Cell Host & Microbe

Mlkl-driven NecroptosisReceptor Tyrosine KinaseApoptosisViral PathogenesisImmunology +10

Survival Function of the FADD-CASPASE-8-cFLIPL Complex

Christopher P. Dillon, Andrew Oberst, Ricardo Weinlich, +6

Cell Reports