Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients

Jérôme Hadjadj, Nader Yatim, Laura Barnabei, +27

Science

RIPK1 and NF-κB signaling in dying cells determines cross-priming of CD8 ⁺ T cells

Nader Yatim, Hélène Jusforgues-Saklani, Susana Orozco, +6

Science

Dipeptidylpeptidase 4 inhibition enhances lymphocyte trafficking, improving both naturally occurring tumor immunity and immunotherapy

Rosa Barreira da Silva, Melissa E. Laird, Nader Yatim, +3

Nature Immunology

Dipeptidylpeptidase 4Cancer ImmunosurveillanceAutoimmune DiseaseImmunologyTumor Immunity +8

Widespread Mitochondrial Depletion via Mitophagy Does Not Compromise Necroptosis

Stephen W. G. Tait, Andrew Oberst, Giovanni Quarato, +12

Cell Reports

MitophagyApoptosisImmunologyPathologyCell Death +15

RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis

Susana Orozco, Nader Yatim, Maggie Werner, +6

Cell Death and Differentiation

Signal TransductionSignaling PathwayCell RegulationApoptosisRipk3 Oligomerization +7

Angiopoietin-2 as a marker of endothelial activation is a good predictor factor for intensive care unit admission of COVID-19 patients

David M. Smadja, Coralie L. Guérin, Richard Chocron, +20

Angiogenesis

Impaired type I interferon activity and exacerbated inflammatory responses in severe Covid-19 patients

Jérôme Hadjadj, Nader Yatim, Laura Barnabei, +27

ImmunodeficienciesImmunologySevere Covid-19 PatientsImmune SystemCovid-19 +17

Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency

Evangelos Giampazolias, Barbara Zunino, Sandeep Dhayade, +24

Nature Cell Biology

Tumor BiologyMitochondrial FunctionCell DeathMitochondrial PermeabilizationMedicine +2

Distinct systemic and mucosal immune responses during acute SARS-CoV-2 infection

Nikaïa Smith, Pedro Gonçalves, Bruno Charbit, +18

Nature Immunology

Critical role for Sec22b-dependent antigen cross-presentation in antitumor immunity

Andrés Alloatti, Derek C. Rookhuizen, Leonel Joannas, +8

The Journal of Experimental Medicine