Ahron Flowers

LAG-3 sustains TOX expression and regulates the CD94/NKG2-Qa-1b axis to govern exhausted CD8 T cell NK receptor expression and cytotoxicity

Shin Foong Ngiow, Sasikanth Manne, Yinghui Huang et al. · Cell · 2024 · 98 citations · Full text

Life Sciences, Cell Biology, Immunology +14

Combination anti-PD-1 and anti-CTLA-4 therapy generates waves of clonal responses that include progenitor-exhausted CD8+ T cells

Kevin Wang, Paulina Coutifaris, David Brocks et al. · Cancer Cell · 2024 · 96 citations · Full text

Life Sciences, Immunology, Oncology +16

Patient-derived melanoma organoid models facilitate the assessment of immunotherapies

Lingling Ou, Shujing Liu, Huaishan Wang et al. · EBioMedicine · 2023 · 87 citations · Full text

Medicine, Immunology, Oncology +17

Upregulation of exosome secretion from tumor-associated macrophages plays a key role in the suppression of anti-tumor immunity

Wenqun Zhong, Youtao Lu, Xuexiang Han et al. · Cell Reports · 2023 · 76 citations · Full text

Life Sciences, Cell Biology, Immunology +17

An autologous humanized patient-derived-xenograft platform to evaluate immunotherapy in ovarian cancer

Sarah B. Gitto, Hyoung Kim, Stavros Rafail et al. · Gynecologic Oncology · 2019 · 51 citations

Medicine, Immunology, Oncology +10