David Brocks

Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells

Dagmar Walter, Amelie Lier, Anja Geiselhart et al. · Nature · 2015 · 607 citations

Genome Instability, Cell Division, Haematopoietic Stem Cells +8

Identification of Regulatory Networks in HSCs and Their Immediate Progeny via Integrated Proteome, Transcriptome, and DNA Methylome Analysis

Nina Cabezas‐Wallscheid, Daniel Klimmeck, Jenny Hansson et al. · Cell stem cell · 2014 · 533 citations · Full text

Chromatin, Integrated Proteome, Developmental Biology +12

DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia

Christopher C. Oakes, Marc Seifert, Yassen Assenov et al. · Nature Genetics · 2016 · 305 citations

Hematological Malignancy, Chromatin, Chronic Lymphocytic Leukemia +10

DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats

David Brocks, Christopher R. Schmidt, Michael Daskalakis et al. · Nature Genetics · 2017 · 304 citations · Full text

Chromatin, Transcriptional Regulation, Hdac Inhibitors +12

Intratumor DNA Methylation Heterogeneity Reflects Clonal Evolution in Aggressive Prostate Cancer

David Brocks, Yassen Assenov, Sarah Minner et al. · Cell Reports · 2014 · 265 citations · Full text

Chromatin, Unified Evolutionary Process, Tumor Heterogeneity +13