Kenneth R. Maksimchuk

Identifying and Visualizing Functional PAM Diversity across CRISPR-Cas Systems

Ryan T. Leenay, Kenneth R. Maksimchuk, Rebecca Slotkowski et al. · Molecular Cell · 2016 · 349 citations · Full text

Bioinformatics, Engineering, Crispr-cas Systems +9

Nucleic acid polymerases use a general acid for nucleotidyl transfer

Christian Castro, Eric D. Smidansky, Jamie J. Arnold et al. · Nature Structural & Molecular Biology · 2009 · 219 citations · Full text

Polymerase Chain Reaction, Nucleic Acid Chemistry, Natural Sciences +6

Two proton transfers in the transition state for nucleotidyl transfer catalyzed by RNA- and DNA-dependent RNA and DNA polymerases

Christian Castro, Eric D. Smidansky, Kenneth R. Maksimchuk et al. · Proceedings of the National Academy of Sciences · 2007 · 153 citations · Full text

Viral Replication, Engineering, Proton-coupled Electron Transfer +19

GSK1838705A inhibits the insulin-like growth factor-1 receptor and anaplastic lymphoma kinase and shows antitumor activity in experimental models of human cancers

Peter Sabbatini, Susan Korenchuk, Jason L. Rowand et al. · Molecular Cancer Therapeutics · 2009 · 98 citations · Full text

Antitumor Activity, Immunology, Glucose Homeostasis +16

Motif D of Viral RNA-Dependent RNA Polymerases Determines Efficiency and Fidelity of Nucleotide Addition

Xiaorong Yang, Eric D. Smidansky, Kenneth R. Maksimchuk et al. · Structure · 2012 · 94 citations · Full text

Motif D, Viral Replication, Engineering +9