Christian Castro

Hepatitis C Virus RNA-dependent RNA Polymerase (NS5B) as a Mediator of the Antiviral Activity of Ribavirin

David Maag, Christian Castro, Zhi Hong et al. · Journal of Biological Chemistry · 2001 · 279 citations · Full text

Nucleic acid polymerases use a general acid for nucleotidyl transfer

Christian Castro, Eric D. Smidansky, Jamie J. Arnold et al. · Nature Structural & Molecular Biology · 2009 · 219 citations · Full text

Polymerase Chain Reaction, Nucleic Acid Chemistry, Natural Sciences +6

A Novel Mechanism to Ensure Terminal Initiation by Hepatitis C Virus NS5B Polymerase

Zhi Hong, Craig E. Cameron, Michelle Walker et al. · Virology · 2001 · 181 citations

Novel Mechanism, Viral Replication, Molecular Virology +11

Two proton transfers in the transition state for nucleotidyl transfer catalyzed by RNA- and DNA-dependent RNA and DNA polymerases

Christian Castro, Eric D. Smidansky, Kenneth R. Maksimchuk et al. · Proceedings of the National Academy of Sciences · 2007 · 153 citations · Full text

Viral Replication, Engineering, Proton-coupled Electron Transfer +19

Structural and functional characterization of the coxsackievirus B3 CRE(2C): role of CRE(2C) in negative- and positive-strand RNA synthesis

Mark J. M. van Ooij, Dorothee A. Vogt, Aniko V. Paul et al. · Journal of General Virology · 2005 · 93 citations