Joseph R. Hedde

Altered functional brain network connectivity and glutamate system function in transgenic mice expressing truncated Disrupted-in-Schizophrenia 1

Neil Dawson, Masaki Kurihara, David M. Thomson et al. · Translational Psychiatry · 2015 · 38 citations · Full text

Identification and Profiling of a Selective and Brain Penetrant Radioligand for in Vivo Target Occupancy Measurement of Casein Kinase 1 (CK1) Inhibitors

Travis T. Wager, Paul Galatsis, Ramalakshmi Y. Chandrasekaran et al. · ACS Chemical Neuroscience · 2017 · 25 citations

The isozyme selective phosphodiesterase-4 inhibitor, ABI-4, attenuates the effects of lipopolysaccharide in human cells and rodent models of peripheral and CNS inflammation

Joseph R. Hedde, Ashley N. Hanks, Christopher J. Schmidt et al. · Brain Behavior and Immunity · 2017 · 24 citations

Inflammation, Anti-inflammatory, Autoimmune Disease +11

Discovery of Potent, Selective, and Brain-Penetrant Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibitors that Modulate Brain Inflammation <i>In Vivo</i>

J. Howard Jones, Zhili Xin, Martin Himmelbauer et al. · Journal of Medicinal Chemistry · 2021 · 14 citations · Full text