David Maliňák

Tacrine–Trolox Hybrids: A Novel Class of Centrally Active, Nonhepatotoxic Multi-Target-Directed Ligands Exerting Anticholinesterase and Antioxidant Activities with Low In Vivo Toxicity

Eugenie Nepovimová, Jan Korábečný, Rafael Doležal et al. · Journal of Medicinal Chemistry · 2015 · 127 citations · Full text

Tacrine-trolox Hybrids, Tacrine–trolox Hybrids, Medicinal Chemistry +15

Pyridinium Oximes with<i>Ortho</i>-Positioned Chlorine Moiety Exhibit Improved Physicochemical Properties and Efficient Reactivation of Human Acetylcholinesterase Inhibited by Several Nerve Agents

Tamara Zorbaz, David Maliňák, Nikola Maraković et al. · Journal of Medicinal Chemistry · 2018 · 62 citations · Full text

Towards understanding the mechanism of action of antibacterial N-alkyl-3-hydroxypyridinium salts: Biological activities, molecular modeling and QSAR studies

Rafael Doležal, Ondřej Soukup, David Maliňák et al. · European Journal of Medicinal Chemistry · 2016 · 58 citations

Qsar Studies, Medicinal Chemistry, Biochemistry +12

7-Methoxytacrine-p-Anisidine Hybrids as Novel Dual Binding Site Acetylcholinesterase Inhibitors for Alzheimer’s Disease Treatment

Jan Korábečný, Martin Andrš, Eugenie Nepovimová et al. · Molecules · 2015 · 44 citations · Full text

Neurochemical Biomarkers, 7-Methoxytacrine-p-anisidine Hybrids, Pharmaceutical Chemistry +19

6-Hydroxyquinolinium salts differing in the length of alkyl side-chain: Synthesis and antimicrobial activity

David Maliňák, Rafael Doležal, Jan Marek et al. · Bioorganic & Medicinal Chemistry Letters · 2014 · 43 citations

Medicinal Chemistry, Bioorganic Chemistry, Biochemistry +10