Lance Heinle

Development of an in vitro drug–drug interaction assay to simultaneously monitor five cytochrome P450 isoforms and performance assessment using drug library compounds

Michael Zientek, Howard Miller, Danielle Smith et al. · Journal of Pharmacological and Toxicological Methods · 2008 · 61 citations

Medicine, Pharmacokinetics, Pharmacology +14

Mathematical and Experimental Validation of Flux Dialysis Method: An Improved Approach to Measure Unbound Fraction for Compounds with High Protein Binding and Other Challenging Properties

J. Cory Kalvass, Colin Phipps, Gary J. Jenkins et al. · Drug Metabolism and Disposition · 2018 · 57 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

A High Throughput, 384-Well, Semi-Automated, Hepatocyte Intrinsic Clearance Assay for Screening New Molecular Entities in Drug Discovery

Lance Heinle, Vincent Peterkin, Sonia de Morais et al. · Combinatorial Chemistry & High Throughput Screening · 2015 · 14 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

A homologous series of internal standards for near universal application in the discovery LC-MS/MS bioanalytical laboratory

Lance Heinle, Kristin Sulaiman, Amanda M. Olson et al. · Journal of Pharmaceutical and Biomedical Analysis · 2020 · 14 citations

Pharmacy, Pharmaceutical Analysis, Analytical Chemistry +16