Howard Miller

Physicochemical Space for Optimum Oral Bioavailability: Contribution of Human Intestinal Absorption and First-Pass Elimination

Manthena V. S. Varma, R. Scott Obach, Charles J. Rotter et al. · Journal of Medicinal Chemistry · 2010 · 314 citations

Nutrition, Pharmaceutical Science, Oral Bioavailability +19

Physicochemical Determinants of Human Renal Clearance

Manthena V. S. Varma, Bo Feng, R. Scott Obach et al. · Journal of Medicinal Chemistry · 2009 · 205 citations

Nannocystin A: an Elongation Factor 1 Inhibitor from Myxobacteria with Differential Anti‐Cancer Properties

Philipp Krastel, Silvio Roggo, Markus Schirle et al. · Angewandte Chemie International Edition · 2015 · 106 citations

CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing’s sarcoma

Nathan T. Ross, Felix Lohmann, Seth Carbonneau et al. · Nature Chemical Biology · 2019 · 85 citations · Full text

Transcriptional Regulation, Medicine, Cancer Cell Biology +9

Development of an in vitro drug–drug interaction assay to simultaneously monitor five cytochrome P450 isoforms and performance assessment using drug library compounds

Michael Zientek, Howard Miller, Danielle Smith et al. · Journal of Pharmacological and Toxicological Methods · 2008 · 61 citations

Therapeutic Drug Monitoring, Preclinical Drug Evaluation, Biochemistry +11