Danielle Smith

Development of an in vitro drug–drug interaction assay to simultaneously monitor five cytochrome P450 isoforms and performance assessment using drug library compounds

Michael Zientek, Howard Miller, Danielle Smith et al. · Journal of Pharmacological and Toxicological Methods · 2008 · 61 citations

Therapeutic Drug Monitoring, Preclinical Drug Evaluation, Biochemistry +11

Analytical approaches to determine cytochrome P450 inhibitory potential of new chemical entities in drug discovery

Danielle Smith, Nalini Sadagopan, Michael Zientek et al. · Journal of Chromatography B · 2006 · 50 citations

Medicinal Chemistry, New Chemical Entities, Drug Target +12

Validation of a semi-automated human hepatocyte assay for the determination and prediction of intrinsic clearance in discovery

Anita Reddy, Tycho Heimbach, Sascha Freiwald et al. · Journal of Pharmaceutical and Biomedical Analysis · 2004 · 28 citations

Pathology, Intrinsic Clearance, Bioanalysis +16

Evaluation of an integrated in vitro–in silico PBPK (physiologically based pharmacokinetic) model to provide estimates of human bioavailability

Hongliang Cai, Chad Stoner, Anita Reddy et al. · International Journal of Pharmaceutics · 2005 · 24 citations

Physiologically Based Pharmacokinetics, Pharmacokinetic Modeling, Vitro–in Silico Pbpk +8

Quantitative analysis of PD 0332991 in mouse plasma using automated micro-sample processing and microbore liquid chromatography coupled with tandem mass spectrometry

Danielle Smith, Max Tella, Sadayappan V. Rahavendran et al. · Journal of Chromatography B · 2011 · 19 citations

Engineering, Biochemistry, Bioanalysis +11