Tyler J. Reich

Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells

Joseph A. Fraietta, Christopher L. Nobles, Morgan A. Sammons et al. · Nature · 2018 · 829 citations · Full text

Cd19-targeted T Cells, Cancer Immunosurveillance, Immunology +8

Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell

Marco Ruella, Jun Xu, David M. Barrett et al. · Nature Medicine · 2018 · 620 citations · Full text

Autoimmune Disease, Immunology, Antigen Processing +5

BET bromodomain protein inhibition reverses chimeric antigen receptor extinction and reinvigorates exhausted T cells in chronic lymphocytic leukemia

Weimin Kong, Alexander J. Dimitri, Wang Wenliang et al. · Journal of Clinical Investigation · 2021 · 87 citations · Full text

Chronic Lymphocytic Leukemia, T-regulatory Cell, Immunology +16

Cars in Leukemia: Relapse with Antigen-Negative Leukemia Originating from a Single B Cell Expressing the Leukemia-Targeting CAR

Simon F. Lacey, Jun Xu, Marco Ruella et al. · Blood · 2016 · 18 citations

Lymphocyte lineage-specific and developmental stage specific mechanisms suppress cyclin D3 expression in response to DNA double strand breaks

Amy DeMicco, Tyler J. Reich, Rahul Singh Arya et al. · Cell Cycle · 2016 · 13 citations · Full text

Lymphocyte Development, Genetics, T-regulatory Cell +23