Mario van Zeeland

X-ray structure of p38α bound to TAK-715: comparison with three classic inhibitors

Rita Azevedo, Mario van Zeeland, H.C.A. Raaijmakers et al. · Acta Crystallographica Section D Biological Crystallography · 2012 · 37 citations · Full text

X-ray Crystallography, Molecular Biology, Inhibit P38α Function +20

Dioxo-triazines as a novel series of cathepsin K inhibitors

Zoran Ranković, Jiaqiang Cai, Xavier Fradera et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 26 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Cathepsin K Inhibitors +11

Design and optimization of a series of novel 2-cyano-pyrimidines as cathepsin K inhibitors

Zoran Ranković, Jiaqiang Cai, Jennifer Kerr et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 25 citations · Full text

Combinatorial Chemistry, Cathepsin K Inhibitors, Medicinal Chemistry +10

Structure-based lead identification of ATP-competitive MK2 inhibitors

Tjeerd Barf, Allard Kaptein, Sander de Wilde et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 22 citations · Full text

Medicinal Chemistry, Hit Identification, Biochemistry +8

4-(3-Trifluoromethylphenyl)-pyrimidine-2-carbonitrile as cathepsin S inhibitors: N3, not N1 is critically important

Jiaqiang Cai, Xavier Fradera, Mario van Zeeland et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 21 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +11