Camilla Göktürk

MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

Helge Gad, Tobias Koolmeister, Ann‐Sofie Jemth et al. · Nature · 2014 · 525 citations

Tumor Biology, Dntp Pool, Mth1 Inhibition +8

Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy

K. Huber, E. Salah, Branka Radic-Sarikas et al. · Nature · 2014 · 387 citations · Full text

Medicinal Chemistry, Drug Targeting, Anticancer Strategy +9

Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation

Torkild Visnes, Armando Cázares‐Körner, Wenjing Hao et al. · Science · 2018 · 220 citations

Validation and development of MTH1 inhibitors for treatment of cancer

Ulrika Warpman Berglund, Kumar Sanjiv, Helge Gad et al. · Annals of Oncology · 2016 · 145 citations · Full text

Oncology, Medicine, Pathology +7

Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress

Nadilly Bonagas, Nina Gustafsson, Martin Henriksson et al. · Nature Cancer · 2022 · 94 citations · Full text