Phil Jeffrey

Central Nervous System Drug Disposition: The Relationship between in Situ Brain Permeability and Brain Free Fraction

Scott Summerfield, Kevin D. Read, David J. Begley et al. · Journal of Pharmacology and Experimental Therapeutics · 2007 · 279 citations

Improving the in Vitro Prediction of in Vivo Central Nervous System Penetration: Integrating Permeability, P-glycoprotein Efflux, and Free Fractions in Blood and Brain

Scott Summerfield, Alexander J. Stevens, Leanne Cutler et al. · Journal of Pharmacology and Experimental Therapeutics · 2006 · 176 citations

5-Chloro-<i>N</i>-(4-methoxy-3-piperazin-1-yl- phenyl)-3-methyl-2-benzothiophenesulfon- amide (SB-271046):  A Potent, Selective, and Orally Bioavailable 5-HT₆ Receptor Antagonist

Steven M. Bromidge, Anthony M. Brown, Stephen E. Clarke et al. · Journal of Medicinal Chemistry · 1999 · 170 citations · Full text

Drug Target, Altmetric Attention Score, 4-Methoxy-3-piperazin-1-yl- Phenyl +18

The Practice of Medicinal Chemistry

Phil Jeffrey · British Journal of Clinical Pharmacology · 2004 · 159 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Pharmaceutical Science +14

Receptor Occupancy and Brain Free Fraction

Jeanette Watson, S. M. Wright, Adam Lucas et al. · Drug Metabolism and Disposition · 2009 · 118 citations