Philipp Schmid

Selective GlyT1 Inhibitors: Discovery of [4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-methanesulfonyl-2-((<i>S</i>)-2,2,2-trifluoro-1-methylethoxy)phenyl]methanone (RG1678), a Promising Novel Medicine To Treat Schizophrenia

Emmanuel Pinard, Alexander Alanine, Daniela Alberati et al. · Journal of Medicinal Chemistry · 2010 · 133 citations · Full text

Psychotropic Medication, Herg Channel Selectivity, Psychopharmacology +18

Mechanistic Studies of Fatty Acid Activation by CYP152 Peroxygenases Reveal Unexpected Desaturase Activity

Mathias Pickl, Sara Kurakin, Fabián G. Cantú Reinhard et al. · ACS Catalysis · 2018 · 98 citations · Full text

Discovery and Characterization of 2-Aminooxazolines as Highly Potent, Selective, and Orally Active TAAR1 Agonists

Guido Galley, Angélica Beurier, Guillaume Décoret et al. · ACS Medicinal Chemistry Letters · 2015 · 50 citations · Full text

Drug Target, Active Taar1 Agonists, Pharmacotherapy +17

A Ligand Selection Strategy Identifies Chemical Probes Targeting the Proteases of SARS‐CoV‐2

Lilian Peñalver, Philipp Schmid, Dávid Szamosvári et al. · Angewandte Chemie International Edition · 2020 · 19 citations · Full text

Discovery of benzoylisoindolines as a novel class of potent, selective and orally active GlyT1 inhibitors

Emmanuel Pinard, Daniela Alberati, Markus Bender et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 17 citations · Full text

Medicinal Chemistry, Drug Target, Biochemistry +10