Haresh Ajani

Unraveling the Structure–Affinity Relationship between Cucurbit[<i>n</i>]urils (<i>n</i> = 7, 8) and Cationic Diamondoids

David Sigwalt, Marina Šekutor, Liping Cao et al. · Journal of the American Chemical Society · 2017 · 87 citations

Natural Sciences, Chemistry, Medicinal Chemistry +13

Malonate-based inhibitors of mammalian serine racemase: Kinetic characterization and structure-based computational study

Barbora Vorlová, Dana Nachtigallová, Jana Jirásková-Vaníčková et al. · European Journal of Medicinal Chemistry · 2014 · 58 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Synthesis and structure–activity relationship of potent, selective and orally active anthranilamide-based factor Xa inhibitors: Application of weakly basic sulfoximine group as novel S4 binding element

Vrajesh B. Pandya, Mukul R. Jain, Ganes Chakrabarti et al. · European Journal of Medicinal Chemistry · 2012 · 42 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Discovery of <i>N</i>²-(4-Amino-cyclohexyl)-9-cyclopentyl-<i>N</i>⁶-(4-morpholin-4-ylmethyl-phenyl)-<i>9H</i>-purine-2,6-diamine as a Potent FLT3 Kinase Inhibitor for Acute Myeloid Leukemia with FLT3 Mutations

Tomáš Gucký, Eva Řezníčková, Tereza Radošová Muchová et al. · Journal of Medicinal Chemistry · 2018 · 42 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Explicit treatment of active-site waters enhances quantum mechanical/implicit solvent scoring: Inhibition of CDK2 by new pyrazolo[1,5-a]pyrimidines

Michaela Hylsová, Benoît Carbain, Jindřich Fanfrlík et al. · European Journal of Medicinal Chemistry · 2016 · 37 citations · Full text

Natural Sciences, Chemistry, Medicinal Chemistry +16