David Wifling

Structural basis of ligand binding modes at the neuropeptide Y Y1 receptor

Zhenlin Yang, Shuo Han, Max Keller et al. · Nature · 2018 · 142 citations · Full text

Biochemistry, G Protein-coupled Receptor, Protein Folding +10

Pandemic Drugs at Pandemic Speed: Infrastructure for Accelerating\n COVID-19 Drug Discovery with Hybrid Machine Learning- and Physics-based\n Simulations on High Performance Computers

Agastya P. Bhati, Shunzhou Wan, Dario Alfè et al. · arXiv (Cornell University) · 2021 · 41 citations · Full text

Mimicking of Arginine by Functionalized<i>N</i>^ω-Carbamoylated Arginine As a New Broadly Applicable Approach to Labeled Bioactive Peptides: High Affinity Angiotensin, Neuropeptide Y, Neuropeptide FF, and Neurotensin Receptor Ligands As Examples

Max Keller, Kilian Kuhn, Jürgen Einsiedel et al. · Journal of Medicinal Chemistry · 2016 · 39 citations · Full text

The Extracellular Loop 2 (ECL2) of the Human Histamine H4 Receptor Substantially Contributes to Ligand Binding and Constitutive Activity

David Wifling, Günther Bernhardt, Stefan Dove et al. · PLoS ONE · 2015 · 35 citations · Full text

Molecular Regulation, Molecular Biology, Extracellular Loop 2 +16

Molecular determinants for the high constitutive activity of the human histamine<scp>H</scp>₄receptor: functional studies on orthologues and mutants

David Wifling, K Löffel, Uwe Nordemann et al. · British Journal of Pharmacology · 2014 · 33 citations · Full text