Donna A. MacDuff

Mitochondrial DNA stress primes the antiviral innate immune response

A. Phillip West, William Khoury-Hanold, Matthew Staron et al. · Nature · 2015 · 1.8K citations · Full text

Inflammation, Autoimmune Disease, Mitochondrial Function +8

Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity

John W. Schoggins, Donna A. MacDuff, Naoko Imanaka et al. · Nature · 2013 · 886 citations · Full text

Host Response, Ifn-induced Genes, Pathogenesis +12

Identification of a candidate therapeutic autophagy-inducing peptide

Sanae Shoji-Kawata, Rhea Sumpter, Matthew Leveno et al. · Nature · 2013 · 750 citations · Full text

Cell Autophagy, Mitophagy, Autoimmune Disease +9

The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy

Robert O. Watson, Samantha L. Bell, Donna A. MacDuff et al. · Cell Host & Microbe · 2015 · 612 citations · Full text

Medical Microbiology, Pulmonary Tuberculosis, Activate Autophagy +11

Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency

Bertrand Boisson, Emmanuel Laplantine, Carolina Prando et al. · Nature Immunology · 2012 · 460 citations · Full text