Global Transcription in Pluripotent Embryonic Stem Cells

Sol Efroni, Radharani Duttagupta, Jill Cheng, +10

Cell stem cell

Embryonic Stem CellTranscriptional RegulationGlobal TranscriptionDevelopmental BiologyInduced Pluripotent Stem Cell +5

IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39

Iván Mascanfroni, Ada Yeste, Sílvio M. Vieira, +10

Nature Immunology

InflammationAutoimmune DiseaseIl-27 ActsT-regulatory CellImmunology +12

The linker histone H1.0 generates epigenetic and functional intratumor heterogeneity

Cristina Morales, Alva Biran, Matthew J. Burney, +13

Science

Histone ModificationsEpigenetic ChangeGeneticsEpigeneticsTumor Biology +17

Tamoxifen-resistant breast cancer cells are resistant to DNA-damaging chemotherapy because of upregulated BARD1 and BRCA1

Yinghua Zhu, Yujie Liu, Chao Zhang, +15

Nature Communications

Toward Rigorous Comprehension of Biological Complexity: Modeling, Execution, and Visualization of Thymic T-Cell Maturation

Sol Efroni, David Harel, Irun R. Cohen

Genome Research

EngineeringLymphocyte DevelopmentToward Rigorous ComprehensionCell DifferentiationInteractive Visualization +18

Genetic Variations at Loci Involved in the Immune Response Are Risk Factors for Hepatocellular Carcinoma

Robert Clifford, Jinghui Zhang, Daoud Meerzaman, +18

Hepatology

Identification of Key Processes Underlying Cancer Phenotypes Using Biologic Pathway Analysis

Sol Efroni, Carl F. Schaefer, Kenneth H. Buetow

PLoS ONE

EngineeringPathologyCancer BiologyGene Expression ProfilingTumor Biology +16

Predicting and affecting response to cancer therapy based on pathway-level biomarkers

Rotem Ben‐Hamo, A. Berger, Nancy Gavert, +10

Nature Communications

Pathway-level BiomarkersTumor BiologyPrognostic BiomarkersCancer TherapyMti Therapy +13

Reactive animation: realistic modeling of complex dynamic systems

Sol Efroni, David Harel, Irun R. Cohen

Computer

Event-driven ArchitectureEngineeringSimulationComplex SystemsIntelligent Systems +15

Fmrp Interacts with Adar and Regulates RNA Editing, Synaptic Density and Locomotor Activity in Zebrafish

Adi Shamay-Ramot, Khen Khermesh, Hagit T. Porath, +8

PLoS Genetics

GeneticsNeurotransmitterGenomic MechanismLocomotor ActivityNeurotransmission +17