Influenza-induced monocyte-derived alveolar macrophages confer prolonged antibacterial protection

Helena Aegerter, Justina Kulikauskaite, Stefania Crotta, +6

Nature Immunology

InflammationProlonged Antibacterial ProtectionImmunologyInfectious Respiratory DiseaseInfluenza Vaccine +2

Chromatin Controls DNA Replication Origin Selection, Lagging-Strand Synthesis, and Replication Fork Rates

Christoph F. Kurat, Joseph T.P. Yeeles, Harshil Patel, +2

Molecular Cell

The linker histone H1.0 generates epigenetic and functional intratumor heterogeneity

Cristina Morales, Alva Biran, Matthew J. Burney, +13

Science

Histone ModificationsEpigenetic ChangeGeneticsEpigeneticsTumor Biology +17

SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair

Nnennaya Kanu, Eva Grönroos, Pierre Martinez, +25

Oncogene

Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD

Graeme Hewitt, Valérie Borel, Sandra Segura‐Bayona, +24

Molecular Cell

ATAD3 gene cluster deletions cause cerebellar dysfunction associated with altered mitochondrial DNA and cholesterol metabolism

Radha Desai, Ann E. Frazier, Romina Durigon, +33

Brain

EngineeringMitochondrial DysfunctionGeneticsGenetic EpidemiologyMolecular Genetics +20

The Scc2–Scc4 complex acts in sister chromatid cohesion and transcriptional regulation by maintaining nucleosome-free regions

Lidia Lopez‐Serra, Gavin Kelly, Harshil Patel, +1

Nature Genetics

ChromatinTranscriptional RegulationSister Chromatid CohesionChromatin StructureChromatin Remodeling +10

Targeting the nucleotide salvage factor DNPH1 sensitizes <i>BRCA</i> -deficient cells to PARP inhibitors

Kasper Fugger, Ilirjana Bajrami, Mariana Silva dos Santos, +11

Science

A systematic benchmark of Nanopore long read RNA sequencing for transcript level analysis in human cell lines

Ying Chen, N. Davidson, Yuk Kei Wan, +42

EngineeringDifferent IsoformsIndividual IsoformsGeneticsMolecular Biology +22

A Role for Chromatin Remodeling in Cohesin Loading onto Chromosomes

Sofía Muñoz, Masashi Minamino, Corella S. Casas-Delucchi, +2

Molecular Cell