Shizuka Hirai

Activation of peroxisome proliferator-activated receptor-alpha stimulates both differentiation and fatty acid oxidation in adipocytes

Tsuyoshi Goto, Jooyoung Lee, Aki Teraminami et al. · Journal of Lipid Research · 2011 · 210 citations · Full text

Various Terpenoids Derived from Herbal and Dietary Plants Function as PPAR Modulators and Regulate Carbohydrate and Lipid Metabolism

Tsuyoshi Goto, Nobuyuki Takahashi, Shizuka Hirai et al. · PPAR Research · 2010 · 191 citations · Full text

Several Herbal Plants, Energy Homeostasis, Various Terpenoids Derived +14

Inhibitory effect of naringenin chalcone on inflammatory changes in the interaction between adipocytes and macrophages

Shizuka Hirai, Young-II Kim, Tsuyoshi Goto et al. · Life Sciences · 2007 · 153 citations

Inflammation, Metabolic Syndrome, Anti-inflammatory +13

Diosgenin present in fenugreek improves glucose metabolism by promoting adipocyte differentiation and inhibiting inflammation in adipose tissues

Taku Uemura, Shizuka Hirai, Noriko Mizoguchi et al. · Molecular Nutrition & Food Research · 2010 · 147 citations

Diosgenin, the Main Aglycon of Fenugreek, Inhibits LXRα Activity in HepG2 Cells and Decreases Plasma and Hepatic Triglycerides in Obese Diabetic Mice

Taku Uemura, Tsuyoshi Goto, Min‐Sook Kang et al. · Journal of Nutrition · 2010 · 139 citations

Metabolic Syndrome, Biochemistry, Medicine +11