Activation of peroxisome proliferator-activated receptor-alpha stimulates both differentiation and fatty acid oxidation in adipocytes

Tsuyoshi Goto, Jooyoung Lee, Aki Teraminami, +6

Journal of Lipid Research

Various Terpenoids Derived from Herbal and Dietary Plants Function as PPAR Modulators and Regulate Carbohydrate and Lipid Metabolism

Tsuyoshi Goto, Nobuyuki Takahashi, Shizuka Hirai, +1

PPAR Research

Several Herbal PlantsEnergy HomeostasisVarious Terpenoids DerivedPpar ModulatorsBiochemistry +12

Inhibitory effect of naringenin chalcone on inflammatory changes in the interaction between adipocytes and macrophages

Shizuka Hirai, Young-II Kim, Tsuyoshi Goto, +5

Life Sciences

InflammationMetabolic SyndromeAnti-inflammatoryMedicinePhysiology +11

Diosgenin present in fenugreek improves glucose metabolism by promoting adipocyte differentiation and inhibiting inflammation in adipose tissues

Taku Uemura, Shizuka Hirai, Noriko Mizoguchi, +10

Molecular Nutrition & Food Research

Diosgenin, the Main Aglycon of Fenugreek, Inhibits LXRα Activity in HepG2 Cells and Decreases Plasma and Hepatic Triglycerides in Obese Diabetic Mice

Taku Uemura, Tsuyoshi Goto, Min‐Sook Kang, +12

Journal of Nutrition

Metabolic SyndromeBiochemistryMedicineLiver PhysiologyDiabetes +9

Red yeast rice extracts suppress adipogenesis by down-regulating adipogenic transcription factors and gene expression in 3T3-L1 cells

Tae‐Il Jeon, Seong Gu Hwang, Shizuka Hirai, +5

Life Sciences

Suppress AdipogenesisTranscriptional RegulationGeneticsMetabolic SignalingGene Regulation +6

Tiliroside, a glycosidic flavonoid, ameliorates obesity-induced metabolic disorders via activation of adiponectin signaling followed by enhancement of fatty acid oxidation in liver and skeletal muscle in obese–diabetic mice

Tsuyoshi Goto, Aki Teraminami, Joo‐Young Lee, +8

The Journal of Nutritional Biochemistry

ObesityMetabolic SyndromeHealth SciencesBiochemistrySkeletal Muscle +10

Bixin regulates mRNA expression involved in adipogenesis and enhances insulin sensitivity in 3T3-L1 adipocytes through PPARγ activation

Nobuyuki Takahashi, Tsuyoshi Goto, Aki Taimatsu, +9

Biochemical and Biophysical Research Communications

Energy HomeostasisTranscriptional RegulationMrna ExpressionSignal Transduction3T3-l1 Adipocytes +10

Citrus auraptene acts as an agonist for PPARs and enhances adiponectin production and MCP-1 reduction in 3T3-L1 adipocytes

Kayo Kuroyanagi, Min‐Sook Kang, Tsuyoshi Goto, +8

Biochemical and Biophysical Research Communications

Molecular PharmacologyCitrus Auraptene ActsMolecular PhysiologySignal TransductionBiochemistry +8

Effect of mushroom polysaccharides from Pleurotus eryngii on obesity and gut microbiota in mice fed a high-fat diet

Nakahara Daiki, Nan Cui, Koichiro Mori, +4

European Journal of Nutrition

ObesityMetabolic SyndromeNutritionMushroom PolysaccharidesPleurotus Eryngii +10