Jürg M. Sommer

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

Catherine S. Manno, Glenn F. Pierce, Valder R. Arruda et al. · Nature Medicine · 2006 · 2.1K citations

Inflammation, Aav-factor Ix, Host Response +11

CD8+ T-cell responses to adeno-associated virus capsid in humans

Federico Mingozzi, Marcela V. Maus, Daniel J. Hui et al. · Nature Medicine · 2007 · 716 citations

Cd8+ T-cell Responses, Immunology, Antiviral Response +5

Phase 3 study of recombinant factor VIII Fc fusion protein in severe hemophilia A

Johnny Mahlangu, Jerry S. Powell, Margaret V. Ragni et al. · Blood · 2013 · 436 citations · Full text

Phase 3 Study of Recombinant Factor IX Fc Fusion Protein in Hemophilia B

Jerry S. Powell, John Pasi, Margaret V. Ragni et al. · New England Journal of Medicine · 2013 · 347 citations · Full text

Effects of transient immunosuppression on adenoassociated, virus-mediated, liver-directed gene transfer in rhesus macaques and implications for human gene therapy

Haiyan Jiang, Linda B. Couto, Susannah Patarroyo‐White et al. · Blood · 2006 · 316 citations · Full text