Linda B. Couto

Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector

Mark A. Kay, Catherine S. Manno, Margaret V. Ragni et al. · Nature Genetics · 2000 · 1K citations

Factor Ix, Immunogenetics, Autoimmune Disease +11

AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B

Catherine S. Manno, Ah Keng Chew, S Hutchison et al. · Blood · 2003 · 743 citations · Full text

Hemophilia B Gene Therapy with a High-Specific-Activity Factor IX Variant

Lindsey A. George, Spencer K. Sullivan, Adam Giermasz et al. · New England Journal of Medicine · 2017 · 736 citations · Full text

Long-term correction of canine hemophilia B by gene transfer of blood coagulation factor IX mediated by adeno-associated viral vector

Roland W. Herzog, Edmund Y. Yang, Linda B. Couto et al. · Nature Medicine · 1999 · 562 citations

Pathogenesis, Hematology, Immunology +9

Effects of transient immunosuppression on adenoassociated, virus-mediated, liver-directed gene transfer in rhesus macaques and implications for human gene therapy

Haiyan Jiang, Linda B. Couto, Susannah Patarroyo‐White et al. · Blood · 2006 · 316 citations · Full text