Ellen De Schrijver

RNA interference-mediated silencing of the fatty acid synthase gene attenuates growth and induces morphological changes and apoptosis of LNCaP prostate cancer cells.

Ellen De Schrijver, Koen Brusselmans, Walter Heyns et al. · PubMed · 2003 · 271 citations

Morphological Changes, Engineering, Fatty Acids +11

RNA Interference–Mediated Silencing of the <i>Acetyl-CoA-Carboxylase-α</i> Gene Induces Growth Inhibition and Apoptosis of Prostate Cancer Cells

Koen Brusselmans, Ellen De Schrijver, Guido Verhoeven et al. · Cancer Research · 2005 · 266 citations · Full text

Fatty acid synthase drives the synthesis of phospholipids partitioning into detergent-resistant membrane microdomains

Johannes V. Swinnen, Paul P. Van Veldhoven, Leen Timmermans et al. · Biochemical and Biophysical Research Communications · 2003 · 253 citations

Biosynthesis, Engineering, Membrane Formation +10

Role of the phosphatidylinositol 3'-kinase/PTEN/Akt kinase pathway in the overexpression of fatty acid synthase in LNCaP prostate cancer cells.

Tine Van de Sande, Ellen De Schrijver, Walter Heyns et al. · PubMed · 2002 · 210 citations

Fatty Acid Synthase, Tumor Biology, Signaling Pathway +16

Epigallocatechin‐3‐gallate is a potent natural inhibitor of fatty acid synthase in intact cells and selectively induces apoptosis in prostate cancer cells

Koen Brusselmans, Ellen De Schrijver, Walter Heyns et al. · International Journal of Cancer · 2003 · 204 citations